“Entrée Capital unveiled a $300M fund prioritizing AI agents, DePIN and regulated Web3 infrastructure.”, — write: www.coindesk.com
The fund will target investments from pre-seed through Series A, backing founders building the foundational layers for mainstream Web3 adoption, the firm said in a Thursday email. Targets include artificial intelligence (AI) agents capable of autonomously managing assets within cryptographic policy frameworks, as well as decentralized physical infrastructure (DePIN) networks and blockchain protocols that use token incentives to coordinate, finance and operate real-world infrastructure.
Entrée says its long history across fintech and crypto — including early bets on Stripe, Rapyd, Mesh and Web3 builders like Gen Labs and Breez — positions it to support founders at the intersection of regulated finance and decentralized networks.
Institutional investors are paying close attention to both AI agents and DePIN because they function as crypto-native counterparts to two of today’s fastest-growing technology pillars: artificial intelligence and cloud computing.
AI agents promise autonomous asset management governed by cryptographic policy frameworks, while DePIN networks extend the cloud model by coordinating and financing physical infrastructure. Together, they offer a pathway to secure, automated and highly scalable digital and real-world utility, aligning with institutions’ broader push into next-generation infrastructure.
- As of October 2025, GoPlus has generated $4.7M in total revenue across its product lines. The GoPlus App is the primary revenue driver, contributing $2.5M (approx. 53%), followed by the SafeToken Protocol at $1.7M.
- GoPlus Intelligence’s Token Security API averaged 717 million monthly calls year-to-date in 2025, with a peak of nearly 1 billion calls in February 2025. Total blockchain-level requests, including transaction simulations, averaged an additional 350 million per month.
- Since its January 2025 launch, the $GPS token has registered over $5B in total spot volume and $10B in derivatives volume in 2025. Monthly spot volume peaked in March 2025 at over $1.1B, while derivatives volume peaked the same month at over $4B.
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CEO Brian Armstrong said top banks are “leaning into this as an opportunity,” signaling Wall Street’s quiet embrace of crypto infrastructure.
- Coinbase is working with major US banks on pilot programs focused on stablecoins, crypto custody and trading, CEO Brian Armstrong said.
- Armstrong called for a Senate vote on the CLARITY Act, a bill aimed at defining rules for crypto market structure.
- He spoke at the New York Times DealBook Summit alongside BlackRock CEO Larry Fink, who said bitcoin serves as a hedge for investors concerned about financial and physical security.
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